PEN-V (TABLETS)

Presentation

PEN-V Tablets: White, scored, circular, tablet; each tablets; contains phenoxymethylpenicillin potassium BP equivalent to 250 mg phenoxymethyplenicillin.

PEN-V Syrup: Bottles containing powder to produce 50 ml of red coloured, raspberry flavored syrup; when reconstituted each 5ml contains

Phenoxymethylpenicillin potassium BP equivalent to 125 mg phenoxymethyipenicillin.

Uses

PEN-V is highly active in wide variety of infectiousdiseases caused by phenoxymethylpenicillin

Susceptible Gram-positive organisms. It is used in the management of infections due to phenoxymethylpenicillin-sensitive organisms in particular streptococci and staphylococci but also including pneumococci, treponema pallidum, clostridia and some strains of neisseria. It is recommended for the therapeutic use in the following conditions:

Pneumococcal infections: Respiratory tract infection of mind to moderate severity and infection in the middle ear and paransal sinuses.

Streptococcal infections:  (except penicillinase-producing strains): Mild infections of the skin and soft tissue sensitive ot penicillin.

Prophylactic uses: It is found to be effective in preventing strepotococcal infection in susceptible hosts.

Also it has provie effective in preventing the recurrence of rheumatic fever and chorea.

Dosage and administration

Adults: 125mg to 500mg every four to six hours depending on the severity of the condition.

Children: 5 to 12 years: 125mr to 250 mg every four to six hours.

1 to 5 years: 125mg every six hours.

Infants: (up to 1 year) 62.5mg every six hours To prevent the recurrence of rheumatic fever doses of 125mg every twelve hourse may be given for a period as suggested by the physician. Ideally, each dose should be given half an hour before or at least three hours after a meal.

FIRIFAM- CAPSULES

Presentation

FIRIFAN 150 Capsules: Brown capsules imprinted ‘FIRIFAM 150 mg; each capsule contains 150mg rifampicin BP.

FIRIFAM 450 Capsules: Maroon capsules imprinted with company logo and FIRIFAM 450mg;  each capsuls contains 450mg fifampicin BP.

Uses

FIRIFAM used in combination with other antituberculous drugs, is indicated in the treatment of all form of tuberculosis, including fresh, advanced, chronic and drug resistant cases. it has been used in the treatment of tuberculous meningitis and in combination with other antileprotics. It is also used in the treatment of leprosy.

Dosage and administration

To prevent the possible emergence of rifampicin- resistat strains of mycobacteria. FIRIFAM shoud always be given with other effective antituberculous drugs. The single dose should preferably be taken on an empty stomach at least helf an hour before food.

Adults: Oral: Based on approximately 8 to 12 mg per kg body weight, the recommended dose of fifampicin is 600 mg daily for patients weighing 50kg and above and 450mg for patients under 50 kg in patients with impaired live function the daily dose should not exceed 8mg per kg body weight.

Children: Children may be given 10 to 20 mg per kg body weight to maximum daily dose of 600 mg.