FIMOXYL- CAPSULES

Presentation

FIMOXYL Capsules: Orange and black capsules imprinted  ‘FIMOXYL 250 mg; each capsule contains amoxycillin trihydrate BP equivalent to 250mg amoxycillin. FIMOXYL Syrup: Bottles containing powder for preparation of 100 ml of yellow coloured, banana flavoured syrup; when reconstituted each 5ml contains amoxycillin trihydrate BP equivalent to 125 mg amoxycillin.

FIMOXYL Paediatric Drops: Bottles containing powder for perparation of 15 ml of yellow coloured, bababa flavoured drops; when reconstituted each 1.25 ml contains amoxcillin trihydrate BP equivalent to 125 mg amoxycillin.

A dropper to measure the 1.25 ml dose is provided. FIMOXYL 250 mg Injectio: Powder in vials containing amoxycillin sodium BP equivalent to 500 mg amoxycillin.

Uses

FIMOXYL is a broad spectrum antibiotic used to treat a wide range of infections caused by susceptible Gram-positive and Gram –negative organisms.

It is indicated for the treatment of the following bacterial infections:

Respiratory tract, ENT infections: Acute and chronic bronchitis, pneumonia, otitis media, sinusitis, tonsillitis, pharyngitis, and laryngitis.

Urinary tract infections: Pyelonephritis, cystitis, and urethritis.

Obstetric and gynaecological infections: Bacteriuria in pergnancy, septic abortion, intra-abdominal sepsis and puerperal sepsis.

Gastro- intestinal infections: Typhoid and paratyphoid.

Skin and soft tissue infections: Cellulitis, infected wounds and adscesses.

Generalised infections: Septicemia, bacterial endocarditis, meningitis, peritonitis and osteomyelitis.

Venereal infections:  Gonorrhea and syphilis.

FIMOXYL may also be used as prophylactic cover for patients at risk of developing endocarditic when undergoing surgery.

Dosage and administration

Usual adult dosage:

Oral: 250mg three times daily increasing to 500 mg three times daily for more severe infections.

Injectables: 250-500 mg IM every 8 hourly (or more frequently, if found necessary by the physician) for moderate infections. 500 mg- 1 g IV every 6 hourly for severe infections.

Usual Children’s dosage:

Oral: 2 to 10 years: Half of the adult dose.

Under two years? 1/4th of the adult dose.

Injectables (upto10 years):50-100mg/kg body. weight IM of IV (depending on the severity) in three to four equal divided doses.

Specific dosage recommendation:

Typhoid and paratyphoid

Aault: 4 g daily in divided doses for 14-21 days.

Children: 100 mg /kg/day in divided doses for 14-21 days

Typhoid Carrier States: 3 to 4 g in divided doses for a minimum of one month.

Syphilis: 250mg every 6 hours for 1 month to 5 months according to the stage of the disease and serological response.

Simple acute Urinary Tract infection: Short course

Therapy: Two 3 g dose with 10-12 hours between the doses.

Meningitis: Adults: 150mg/kg/day IV in equally divided doses.

Children: 100-150 gm/kg/day IV in equally divided doses

Gonorrhoea: A single 3 g dose

Dental abscess( as an adjunct to surgical management): Two 3 g doses with 8 hours between the doses.

Severe or recurrent acute otitis media: 3 to 10 years: 750 gm twice a day for two days may be used as an alternative course of treatment.